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Over a median follow-up of 15.9 months, major adverse cardiovascular events occurred in 3.8% of oral semaglutide patients versus 4.8% with placebo (HR 0.79, 95% CI 0.57-1.11
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A single missed dose will cause a temporary dip in plasma levels but should not significantly disrupt results
Diabetes (2011) 60(4):124657.10.2337/db10-1338 128 ShimasakiTMasakiTMitsutomiKUenoDGotohKChibaSet alThe dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin regulates brown adipose tissue uncoupling protein levels in mice with diet-induced obesity
doi:10.1002/dta.2152
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