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Mitophagy and DR Increasing mitophagy plays a therapeutic role in DR Some researchers incubated human retinal pigment epithelial cell line (ARPE-19) with 15 mM and 50 mM glucose, respectively, and found that ROS increased in the low glucose (15 mM) environment, which did not have a significant effect on apoptosis and cell proliferation

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How to implement: Dosing: 20-40 grams daily (post-workout or as snack) Choose undenatured whey (cold-processed, preserves bioactive peptides) Whey protein isolate (higher protein content, lower lactose) Best sources: Grass-fed whey isolate : Highest cysteine content Undenatured whey concentrate : Preserves immunoglobulins and glutathione precursors Avoid heat-treated : Heat denatures cysteine Timing: Post-workout (supports muscle recovery + glutathione synthesis) Morning (with breakfast) For vegans: Pea protein isolate : Lower in cysteine but can be paired with NAC Hemp protein : Moderate cysteine content Evidence: A randomized trial found that 20 grams of whey protein daily for 3 months increased lymphocyte glutathione by 35% and improved immune markers in HIV patients [15]

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