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Because that figure comes from rodent research, many start patients at the low end (about 5 mcg/kg or a flat 250 mcg) and adjust over one to two weeks
Genetic testing through the PlexusDx Precision Peptide Genetic Test ($298) can also reveal whether your peptide-pathway genetics predispose you to stronger inflammatory responses, helping your provider tailor your protocol
PMCID: PMC6796530
If more than 60% of the meal is retained in the stomach after 2 hours or 10% of the meal is retained after 4 hours, this is indicative of gastroparesis
Third, 85% of people on just 5 mg achieved at least 5% weight loss, demonstrating that even the lowest studied dose produces clinically meaningful results for the vast majority of users
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