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Diabetic retinopathy: I would apply the same restrictions as recommended for GLP-1 RAs (see previous At a glance factsheet ) 8 that is, avoid in people with active retinopathy needing ophthalmology review (usually by ensuring that eye screening is up to date)
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The company is planning another Phase 2b trial to assess multiple monthly doses in obesity with preliminary data expected in ear-end-2025 or early-2026
Here are a few areas where this shows up: Kidney Health Large randomized trials have found that GLP-1 receptor agonists are associated with a reduced risk of chronic kidney disease progression and kidney failure 15
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