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Both drug classes exert pleiotropic effects on metabolic factors, such as obesity and hypertension

Qsiva is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol

There were no other significant differences in oxytocin receptor density between groups in any other high expression oxytocin receptor brain regions, which included prelimbic cortex, anterior olfactory nucleus, nucleus accumbens, lateral septal nucleus, bed nucleus of stria terminalis, ventral reuniens, paraventricular and ventromedial hypothalamic nuclei, hippocampal CA1 and CA2/3 regions and the central amygdaloid nucleus

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The hydrolyzed form is intended to support absorption, skin hydration, and elasticity