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Here's roughly what to expect at each stage
Classic hyperglycemic symptoms: Polydipsia (excessive thirst) Polyuria (frequent urination) and nocturia Polyphagia (excessive hunger) with unexplained weight loss (Type 1) Blurred vision (osmotic lens changes) Fatigue, weakness, malaise Slow wound healing
Trevors overstatement is often flamboyant and easy to spot
In practical terms, men tend to notice their midsection shrinking first
Quick answer: In the Phase 2 clinical trial (Jastreboff et al., 2023, New England Journal of Medicine ), retatrutide was given by once-weekly subcutaneous injection across a 112mg range
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