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The benzyl alcohol component permits multi-dose use over a typical 28-day window

But the dosing regime differs widely from one investigation to another based on the purpose, methodology, and design of the experiment

Journal of Clinical and Aesthetic Dermatology, 2(3), 38

Strategies to minimize reactions include rotating injection sites consistently to avoid repeated trauma to the same area, ensuring the solution is at room temperature before injection (cold injections can increase irritation), injecting slowly rather than quickly, and using a smaller gauge needle for less tissue trauma

M., Mahmoud, A.E.E.-R., & Elkhatib, W