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The pivotal programs are public, the STEP trials for semaglutide in weight management ( The New England Journal of Medicine , 2021), SURMOUNT for tirzepatide in weight management (NEJM, 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM, 2024)
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In contrast, the remaining analyses of MOF revealed fracture risks that are comparable between DPP-4i users and GLP-1 RA users
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